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Treating non-healing bone fractures with stem cells

A new device that can rapidly concentrate and extract young cells from irrigation fluid used during orthopaedic surgery holds promise for improving the delivery of stem cell therapy in cases of...

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Stem cells derived from amniotic tissues have immunosuppressive properties

Stem cells derived from human amnion have for some time been considered promising for cell therapies because of their ease of access, ability to differentiate, and absence of ethical issues. Now, a...

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Infants with rare bone disease improve bone formation after cell transplantation

Recent research carried out by a team of researchers in Japan has investigated the use of bone marrow transplants (BMTs) to treat hypophosphatasia (HPP). In this study, the researchers carried out BMT...

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Systemic sclerosis patients with unhealed digital ulcers benefit from fat...

Digital ulcers (DUs) are a frequent, painful, and quality of life altering complication for patients with systemic sclerosis (SSc), a connective tissue disease causing a progressive loss of small blood...

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Small molecule helps get stem cells to sites of disease and damage

Bioengineers from Brigham and Women's Hospital (BWH) with collaborators at the pharmaceutical company Sanofi have identified small molecules that can be used to program stem cells to home in on sites...

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Can 'off the shelf' stem cell therapy treat heart failure patients? UB...

After a heart attack, cardiac stem cell therapy stimulates the growth of new heart cells, but exactly how that happens is unclear. The National Institutes of Health has awarded a $2 million grant to a...

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Recombinant peptide for transplantation of pancreatic islets in mice models...

Fujifilm Corporation has developed the micro-sized petaloid µ-pieces of Recombinant Peptide (RCP), a scaffold material required for cell cultivation and transplantation in regenerative medicine. It has...

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Odd genetic syndrome suggests increased blood vessel resistance could cause...

The culmination of two decades of research, a new study reveals the genetic causes of a curious, rare syndrome that manifests as hypertension (high blood pressure) accompanied by short fingers...

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Lung cell phenotype reverts when seeded onto decellularized lung matrix

Researchers seeded type II lung epithelial cells into a decellularized lung matrix to study their function and report the unexpected finding that instead of differentiating into type I lung cells, they...

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Stem cell therapy for inherited skin blistering

Promising results from a trial of a new stem-cell based therapy for a rare and debilitating skin condition have been published in the Journal of Investigative Dermatology. The therapy, involving...

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Researchers taking bold steps toward engineering new lungs

According to the World Health Organization, chronic obstructive pulmonary disease (COPD) currently affects more than 64 million people worldwide and is poised to become the third leading cause of...

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Most heart muscle cells formed during childhood

New human heart muscle cells can be formed, but this mainly happens during the first ten years of life, according to a new study from Karolinska Institutet in Sweden. Other cell types, however, are...

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Scientists identify a potential new treatment for osteoporosis

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a new therapeutic approach that, while still preliminary, could promote the development of new bone-forming...

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Tuberculosis bacteria hide in the low oxygen niches of bone marrow stem cells

A new study from the Forsyth Institute is helping to shed light on latent tuberculosis and the bacteria's ability to hide in stem cells. Some bone marrow stem cells reside in low oxygen (hypoxia)...

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Stem cell injections improve diabetic neuropathy in animal models

Diabetic neuropathy (DN) is a condition in which perpetually high blood sugar causes nerve damage, resulting in a myriad of symptoms such as numbness, reduced ability to detect painful stimuli, muscle...

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Study reveals bone-building protein's impact on bone stem cells

A new study by UCLA researchers shows that administering the protein NELL-1 intravenously stimulates significant bone formation through the regenerative ability of stem cells.

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Supercharging stem cells to create new therapies

Researchers at the University of Adelaide have discovered a new method for culturing stem cells which sees the highly therapeutic cells grow faster and stronger.

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Stem cell transplant alleviates symptoms in lupus animal models

Systemic lupus erythematosus (SLE) is an autoimmune disease that produces autoantibodies and subsequent immune reactions that can lead to a variety of symptoms, including inflammation of the kidneys,...

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Researchers develop scar-like culture systems to understand and treat fibrosis

A scar might be a reminder of an accident or surgery, but the fibrous tissue that makes up a scar also forms after a heart attack and arises in solid tumors as well as in chronic diseases such as liver...

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Study details 'rotten egg' gas' role in autoimmune disease

The immune system not only responds to infections and other potentially problematic abnormalities in the body, it also contains a built-in brake in the form of regulatory T cells, or Tregs. Tregs...

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